“Knowing It Before Blocking It,” the ABCD of the Peripheral Nerves: Part A (Nerve Anatomy and Physiology)

Regional anesthesia (RA) is an interplay between the local anesthetic (LA) solution and neural structures, resulting in nerve conduction blockade. For that, it necessary to understand which hurdles LA has overcome components of nerves are involved. Background knowledge non-neural helps locate safest area for deposition. In addition, physiology process patterns block onset, involved fibers, regression. Neural connective tissue protects on one hand influences overall effect blockade occurrence injuries other. The arrangement fibers explains science behind differential blockage after This article describes important aspects anatomy (nerve formation composition) (impulse generation propagation). It also provides insight into physiological processes when a damaged structure leads potential clinical symptoms. will help readers sharpen their skills execute safe RA without damaging any vital structures nerve.